[Purpose/significance]Literature weeding plays a positive role in library collection structure optimization and space extension. By referencing the experience and method of the actual weeding work of foreign libraries, it promotes and improves carrying out the scientific weeding work of Chinese libraries.[Method/process]Through understanding the information from the official blogs and CTW (Connecticut College, Trinity College and Wesleyan University) post, the paper introduces and analyzes the Wesleyan University library-weeding project in terms of background, standards, member composition, procedure, and the characters of the program. [Method/process]It summarizes and formulates complete literature weeding measures including feedback mechanism with readers, the involvement of multi-party strength, and the selection of special collections and historical documents, etc.37 It will provide helpful reference for the practical operation, network construction, and development direction of the literature weeding work of Chinese university libraries.